A MICROWAVE ASSISTED GREEN SYNTHESIS, CHARACTERIZATION, AND ANTIMICROBIALSCREENING OF Co(II) AND VO(IV) SCHIFF BASE COMPLEXES DERIVED WITH 2 FURFURALDEHYDE
Cobalt(II) and Vanadium(IV) Schiff base complexes have gained significant research attention due totheir structural versatility, varied catalysis, material, and biomedical applications. This study produced Co(II) andVO(IV) metal complexes utilizing a Schiff base from 2-furfuraldehyde and 3,4-dichloroaniline (FCA) usingreflux and microwave-assisted techniques. The produced compounds were evaluated using physicochemical andspectroscopic methods, viz. elemental analysis. IR, UV–Visible, electron paramagnetic resonance (EPR), molar conductance, magnetic susceptibility, and TGA. The obtained complexes were found to be air- and moisture- stable, crystalline, and intensely colored. Analytical results confirmed a 1:2 (metal-to-ligand) stoichiometryinall complexes. Thermogravimetric studies revealed multi-step decomposition, indicating high thermal stability. The X-ray diffraction (XRD) data provided information on lattice parameters, crystal system, and unit cell dimensions, confirming product crystallisation. The antimicrobial evaluation revealed that the metal complexesexhibited enhanced activity against both bacterial strains (Escherichia coli, Staphylococcus aureus, Streptococcus faecalis) and also against fungal (Trichoderma polysporum, Aspergillus niger, Candida albicans) strains; thus, reflecting their potential biomedical relevance. This research aligns with UNSustainableDevelopment Goal (SDG) 3: Good Health and Well-Being, by contributing to the development of newbioactivecompounds with potential therapeutic applications. Furthermore, the use of microwave-assisted green synthesisdemonstrates a more efficient and environmentally sustainable approach, supporting SDG9: Industry, Innovation, and Infrastructure. Overall, the study provides a foundation for exploring new entities of Schiff basemetal complexes for pharmaceutical and environmental applications.
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