PROCESS INTENSIFICATION AND RSM OPTIMIZATION FOR HIGH-YIELD FRUCTOSE CAPRYLATE SYNTHESIS: THE SYNERGISTIC ROLE OF ULTRASOUND AND IONICLIQUIDS
The production of sugar esters using enzymes is becoming more important as industries move towards usingnontoxic and biodegradable surfactants in food, pharmaceuticals, and cosmetics. This study helps to advance greenchemistry by finding the best way to synthesize fructose caprylate using ultrasound in ionic liquid media. Aspecial method called Box-Behnken Response Surface Methodology was used to create a highly accurate model that showshow ultrasonic energy can overcome traditional limitations and increase conversion rates by 57%comparedtotraditional mechanical stirring methods. This indicates a considerable enhancement, and it's because the ultrasonicenergy helps mass transfer more effectively. Our model is very good at predicting the results, with an R² valueof 99.77% and an adjusted R² value of 99.35%. This research has important effects on the field of sustainable chemical engineering. It shows that using ultrasonic process intensification with ionic liquid and biocatalysis can make greensynthesis faster and more efficient. This study provides a reliable way to improve reaction kinetics in greensynthesis. The study provides essential knowledge for the scaling up of bio-based surfactant production and presentsvalidated optimized production parameters for sustainable production processes.